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(Malanin chain B)
FEATURES
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DESCRIPTION
Also known as MALNB_MALOL. Significantly inhibits growth and induces an apoptotic response in HeLa cells through cell-cycle arrest at S-phase. Exhibits highly cytotoxic activities against cancer cell and non-cancer cell lines producing IC(50) values of 0.15 nM for human cervical carcinoma cells (HeLa), 7.71 nM for rat pheochromocytoma-12 cells (PC-12), 11.20 nM for human breast cancer cells (MCF-7), 15.80 nM for human leukemia cells (K562), 2.79 nM for African green monkey kidney cells (Vero) and 3.92 nM for normal Madin-Darby canine kidney cells (MDCK). Heterodimer of an A chain and a B chain; disulfide-linked.
Also known as MALNB_MALOL. Significantly inhibits growth and induces an apoptotic response in HeLa cells through cell-cycle arrest at S-phase. Exhibits highly cytotoxic activities against cancer cell and non-cancer cell lines producing IC(50) values of 0.15 nM for human cervical carcinoma cells (HeLa), 7.71 nM for rat pheochromocytoma-12 cells (PC- ... More
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Malanin chain B

Molecular Synopsis