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(Conorfamide-Sr2)
FEATURES
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FAMILY
DESCRIPTION
Also known as CRFA2_CONSP. In contrast to other conorfamides, this peptide does not show activity on human and mouse sensory neuron-specific G-protein coupled receptors MRGPRX1 (PubMed:30243794). In vivo, it causes hyperactivity when injected intracranially into mice, and when injected into the foot of the fresh water snail P.paludosa (PubMed:18201803). It also causes paralysis when injected into the foot of the limpet P.opea (PubMed:18201803). Has no effect when injected below the rear part of the dorsal fin of the fish L.reticulatus (PubMed:18201803).
Also known as CRFA2_CONSP. In contrast to other conorfamides, this peptide does not show activity on human and mouse sensory neuron-specific G-protein coupled receptors MRGPRX1 (PubMed:30243794). In vivo, it causes hyperactivity when injected intracranially into mice, and when injected into the foot of the fresh water snail P.paludosa (PubMed:18201 ... More
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Conorfamide-Sr2

Molecular Synopsis