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GTP-binding nuclear protein Ran

Germline Genetics

Summary of germline evidence for RAN and cancer

  • Ensembl Gene ID: ENSG00000132341
  • Ensembl Transcript ID/s: ENST00000392369; ENST00000543796
  • Entrez Gene ID: 5901
  • HGNC Gene Symbol: RAN

Genome-wide association studies

RAN maps to cancer-SNP associations according to the following annotations:

SNPLocusPosition (b37)Risk alleleRAFP-valueEffect sizeCICancerPMIDCatalogTADLSDEPICT
1667_rs111696067 12q24.33 133376540 rs111696067-A 0.59 4E-8 1.1904762 [1.12-1.27] Non-glioblastoma glioma 26424050 https://www.ebi.ac.uk/gwas/search?query=rs111696067 12:130860000-133851895 - -