Pdxp logo
Pdxp (Pyridoxal phosphate phosphatase)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as PLPP_MOUSE, Pdxp, Cin, Plp, Plpp. Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine (By similarity). Pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP (By similarity) (PubMed:24338473, PubMed:24338687). Homodimer.
Also known as PLPP_MOUSE, Pdxp, Cin, Plp, Plpp. Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-t ...
Pdxp logo

Pdxp

Pyridoxal phosphate phosphatase

Molecular Synopsis

LIGANDABILITY
APPROVED DRUGS
No approved drugs found
INVESTIGATIONAL DRUGS
No investigational drugs found
CHEMICAL PROBES
Probe Miner logo
Chemical Probes logo
NETWORK-BASED
CANCER SCORE
No score found
OTHER DISEASES SCORE
No score found
CHEMISTRY-BASED
CHEMISTRY-BASED SCORE
No score found