FEATURES

FAMILY

DESCRIPTION

Also known as AL3A2_HUMAN, ALDH3A2, ALDH10, FALDH. Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length (PubMed:9133646, PubMed:22633490, PubMed:25047030, PubMed:18035827, PubMed:9662422, PubMed:18182499). Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (PubMed:22633490). Homodimer.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

ALDH3A2

Aldehyde dehydrogenase family 3 member A2

ligandability Mutations

ALDH3A2

Molecular Synopsis