FEN1 (Flap endonuclease 1)
FEATURES
Loading...
DESCRIPTION
Loading...
EXTERNAL LINKS
Loading...
Germline Genetics

Summary of germline evidence for FEN1 and cancer

  • Ensembl Gene ID: ENSG00000168496
  • Ensembl Transcript ID/s: ENST00000305885
  • Entrez Gene ID: 2237
  • HGNC Gene Symbol: FEN1

COSMIC germline cancer gene census

Annotated as containing mutations that have been causally implicated in development of the following cancer types: breast cancer.

Genome-wide association studies

FEN1 maps to cancer-SNP associations according to the following annotations:

SNPLocusPosition (b37)Risk alleleRAFP-valueEffect sizeCICancerPMIDCatalogTADLSDEPICT
2728_rs17459411q12.261619829rs174594-ANR2E-131.134[1.097-1.172]Colorectal cancer29471430https://www.ebi.ac.uk/gwas/search?query=rs17459411:61500000-62020000r2>0.9 (11:61543499-61624181)-
787_rs17454911q12.261571382rs174549-?0.591E-201.37[1.28-1.47]Laryngeal squamous cell carcinoma25194280https://www.ebi.ac.uk/gwas/search?query=rs17454911:61500000-62020000r2>0.9 (11:61126521-61788062)YES
1488_rs17453711q12.261552680rs174537-G0.599E-211.16[1.12-1.19]Colorectal cancer24836286https://www.ebi.ac.uk/gwas/search?query=rs17453711:61500000-62020000r2>0.9 (11:61069686-61788062)-
979_rs17453711q12.261552680rs174537-G0.599E-211.16[1.12-1.19]Colorectal cancer26965516https://www.ebi.ac.uk/gwas/search?query=rs17453711:61500000-62020000r2>0.9 (11:61069686-61788062)-
Rows per page:
1-4 of 4