FEATURES

FAMILY

DESCRIPTION

Also known as PURT_ECOLI, purT. Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. PurT is also able to cleave acetyl phosphate and carbamoyl phosphate to produce ATP with acetate and carbamate, respectively. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

purT

Formate-dependent phosphoribosylglycinamide formyltransferase

purT

Molecular Synopsis