HOXA9 logo
HOXA9 (Homeobox protein Hox-A9)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as HXA9_HUMAN, HOXA9, HOX1G. Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. Transiently interacts with PRMT5 in TNF-alpha stimulated endothelial cells.
Also known as HXA9_HUMAN, HOXA9, HOX1G. Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. Transiently interacts wi ...
HOXA9 logo

HOXA9

Homeobox protein Hox-A9

Germline Genetics

Summary of germline evidence for HOXA9 and cancer

  • Ensembl Gene ID: ENSG00000078399
  • Ensembl Transcript ID/s: ENST00000343483
  • Entrez Gene ID: 3205
  • HGNC Gene Symbol: HOXA9

Genome-wide association studies

HOXA9 maps to cancer-SNP associations according to the following annotations:

SNPLocusPosition (b37)Risk alleleRAFP-valueEffect sizeCICancerPMIDCatalogTADLSDEPICT
1791_rs10486567 7p15.1 27976563 rs10486567-G 0.77 3E-11 1.17 [1.12-1.22] Prostate cancer 26034056 https://www.ebi.ac.uk/gwas/search?query=rs10486567 7:27220000-28220000 - -
1764_rs10486567 7p15.1 27976563 rs10486567-G 0.77 3E-9 1.17 [1.11-1.23] Prostate cancer 26034056 https://www.ebi.ac.uk/gwas/search?query=rs10486567 7:27220000-28220000 - -
1778_rs7808935 7p15.1 27977363 rs7808935-T 0.766 3E-11 1.17 [1.12-1.22] Prostate cancer 26034056 https://www.ebi.ac.uk/gwas/search?query=rs7808935 7:27220000-28220000 - -