HOXA9 logo
HOXA9 (Homeobox protein Hox-A9)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as HXA9_HUMAN, HOXA9, HOX1G. Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. Transiently interacts with PRMT5 in TNF-alpha stimulated endothelial cells.
Also known as HXA9_HUMAN, HOXA9, HOX1G. Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. Transiently interacts wi ...
HOXA9 logo

HOXA9

Homeobox protein Hox-A9

Copy number variation

DiseaseSignal Cell linesGain Cell linesAvg. ampLoss Cell linesAvg. lossNo-signal Cell linesAvg. change
cancer 1 1 1.86 0 146 1.19
NS 1 1 1.88 0 152 1.19
carcinoma 5 4 1.91 1 0.32 547 1.21
haematopoietic_neoplasm 0 0 0 63 1.01
leukaemia 0 0 0 84 1.01
lymphoid_neoplasm 0 0 0 135 1.12
glioma 0 0 0 52 1.46
malignant_melanoma 0 0 0 56 1.33
melanoma 0 0 0 43 1.37
glioblastoma 0 0 0 2 1.26

Cell lines

Cell lineSignalCopy numberAvg. genome ploidyAmplificationDiseaseTissue
22Rv-1 No signal 2 2.04 0.98 cancer, NS, carcinoma prostate
5637 No signal 4 2.99 1.34 cancer, carcinoma bladder, urinary_tract
639-V No signal 4 2.41 1.66 cancer, carcinoma bladder, ureter, urinary_tract
647-V No signal 4 2.50 1.60 cancer, carcinoma bladder, urinary_tract
697 No signal 2 1.98 1.01 haematopoietic_neoplasm, leukaemia, lymphoid_neoplasm blood_bone_marrow, haematopoietic_and_lymphoid_tissue
769-P No signal 2 1.97 1.02 carcinoma kidney
786-0 No signal 5 3.82 1.31 cancer, carcinoma kidney
8-MG-BA No signal 4 2.20 1.82 glioma brain, central_nervous_system
8305C Loss 1 3.09 0.32 carcinoma thyroid
8505C No signal 4 3.00 1.33 carcinoma thyroid