Also known as EDNRA_HUMAN, EDNRA, ETA, ETRA. Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. Interacts with HDAC7 and KAT5.
