FEATURES

FAMILY

DESCRIPTION

Also known as AOFA_HUMAN, MAOA. Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

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EXTERNAL LINKS

MAOA

Amine oxidase [flavin-containing] A

ligandability Mutations

MAOA

Molecular Synopsis