FEATURES

FAMILY

DESCRIPTION

Also known as VATB2_HUMAN, ATP6V1B2, ATP6B2, VPP3. Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

ATP6V1B2

V-type proton ATPase subunit B, brain isoform

ligandability Mutations

ATP6V1B2

Molecular Synopsis