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FEATURES

FAMILY

TPP enzyme family

DESCRIPTION

Also known as MEND_ECOLI, menD. Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Homodimer.

Also known as MEND_ECOLI, menD. Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphat ...

EXTERNAL LINKS

uniprot
enzyme classification

menD

2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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