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SEC2 (Rab guanine nucleotide exchange factor SEC2)
FEATURES
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FAMILY
DESCRIPTION
Also known as SEC2_YEAST, SEC2. Guanine nucleotide exchange factor for SEC4, catalyzing the dissociation of GDP from SEC4 and also potently promoting binding of GTP. Activation of SEC4 by SEC2 is needed for the directed transport of vesicles to sites of exocytosis. Binds the Rab GTPase YPT32, but does not have exchange activity on YPT32. Interacts with SEC4. Interacts with YPT32, preferentially in its GTP-bound form.
Also known as SEC2_YEAST, SEC2. Guanine nucleotide exchange factor for SEC4, catalyzing the dissociation of GDP from SEC4 and also potently promoting binding of GTP. Activation of SEC4 by SEC2 is needed for the directed transport of vesicles to sites of exocytosis. Binds the Rab GTPase YPT32, but does not have exchange activity on YPT32. Interacts ... More
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SEC2

Rab guanine nucleotide exchange factor SEC2

Molecular Synopsis