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UL98 (Alkaline nuclease)
FEATURES
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FAMILY
DESCRIPTION
Also known as AN_HCMVA, UL98. Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules. Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate. Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides. Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity. Interacts with major DNA-binding protein; this interaction increases the nuclease processivity of the alkaline exonuclease.
Also known as AN_HCMVA, UL98. Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules. Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate. Exonuclease digestion of ... More
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UL98

Alkaline nuclease

Molecular Synopsis