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RPB3 (DNA-directed RNA polymerase II subunit RPB3)
FEATURES
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FAMILY
DESCRIPTION
Also known as RPB3_YEAST, RPB3. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft. Seems to be involved in transcription termination. Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
Also known as RPB3_YEAST, RPB3. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machine ...
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RPB3

DNA-directed RNA polymerase II subunit RPB3

Molecular Synopsis

LIGANDABILITY
APPROVED DRUGS
No approved drugs found
INVESTIGATIONAL DRUGS
No investigational drugs found
CHEMICAL PROBES
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NETWORK-BASED
CANCER SCORE
No score found
OTHER DISEASES SCORE
No score found
CHEMISTRY-BASED
CHEMISTRY-BASED SCORE
No score found