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Hnf1a (Hepatocyte nuclear factor 1-alpha)
FEATURES
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FAMILY
DESCRIPTION
Also known as HNF1A_RAT, Hnf1a, Hnf-1, Hnf-1a, Tcf1. Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity). Binds DNA as a dimer (PubMed:8491173). Heterotetramer with PCBD1; formed by a dimer of dimers (By similarity). Interacts with PCBD1 (By similarity). Interacts with BHLHE41 (By similarity).
Also known as HNF1A_RAT, Hnf1a, Hnf-1, Hnf-1a, Tcf1. Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity). Binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity). Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similar ... More
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Hnf1a

Hepatocyte nuclear factor 1-alpha

Molecular Synopsis