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gag (Gag polyprotein)
FEATURES
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DESCRIPTION
Also known as GAG_HTL1M, gag. The matrix domain targets Gag, Gag-Pro and Gag-Pro-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus., Matrix protein., Forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex., Binds strongly to viral nucleic acids and promote their aggregation. Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs. Gag polyprotein: Homodimer; the homodimers are part of the immature particles. Gag polyprotein: Interacts with human TSG101 and NEDD4; these interactions are essential for budding and release of viral particles. Matrix protein p19: Homodimer; further assembles as homohexamers.
Also known as GAG_HTL1M, gag. The matrix domain targets Gag, Gag-Pro and Gag-Pro-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus., Matrix protein., Forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex., Binds strongly to viral nucl ... More
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gag

Gag polyprotein

Molecular Synopsis