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EJRF1 (mRNA export factor ICP27 homolog)
FEATURES
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FAMILY
DESCRIPTION
Also known as ICP27_SHV21, EJRF1. Probably acts as a viral splicing factor that regulates viral RNA splicing. Functions as a multifunctional regulator of the expression of viral lytic genes (By similarity). Early protein that promotes the accumulation and nuclear export of viral intronless RNA transcripts by interacting with mRNAs and cellular export proteins. Homodimer. Homodimerization is required for transactivation (By similarity). Interacts with host ALYREF and with mouse ALYREF2. Associates in a complex with RNA, and host export factors NXF1/TAP and ALYREF or ALYREF2; these interactions allow nuclear export of viral transcripts.
Also known as ICP27_SHV21, EJRF1. Probably acts as a viral splicing factor that regulates viral RNA splicing. Functions as a multifunctional regulator of the expression of viral lytic genes (By similarity). Early protein that promotes the accumulation and nuclear export of viral intronless RNA transcripts by interacting with mRNAs and cellular expo ... More
EJRF1 logo

EJRF1

mRNA export factor ICP27 homolog

Molecular Synopsis