FEATURES

FAMILY

class-II pyridoxal-phosphate-dependent aminotransferase family

DESCRIPTION

Also known as BIOF_ECOLI, bioF. Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate, but it is believed that pimeloyl-ACP rather than pimeloyl-CoA is the physiological substrate of BioF. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

bioF

8-amino-7-oxononanoate synthase

bioF

Molecular Synopsis