FEATURES

FAMILY

DESCRIPTION

Also known as MYH7_HUMAN, MYH7, MYHCB. Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with ECPAS (PubMed:20682791). Interacts (via C-terminus) with LRRC39 (PubMed:20847312).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MYH7

Myosin-7

MYH7

Molecular Synopsis