FEATURES

FAMILY

DESCRIPTION

Also known as ACM1_HUMAN, CHRM1. The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Interacts with GPRASP2 (PubMed:15086532). Interacts with TMEM147 (PubMed:21056967).

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

CHRM1

Muscarinic acetylcholine receptor M1

ligandability Mutations

CHRM1

Molecular Synopsis