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(A type blood N-acetyl-alpha-D-galactosamine deacetylase)
FEATURES
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DESCRIPTION
Also known as ADAC_FLAPL. One of an enzyme pair that work together to convert the A antigen to the H antigen of the O blood type, which together release galactosamine. Catalyzes the first step in the conversion, generating the substrate for the subsequent enzyme (FpGalNase, AC P0DTR5). Works on many different A antigen subtypes. Glu-90 probably activates a nucleophilic water molecule to start the deacetylation reaction.
Also known as ADAC_FLAPL. One of an enzyme pair that work together to convert the A antigen to the H antigen of the O blood type, which together release galactosamine. Catalyzes the first step in the conversion, generating the substrate for the subsequent enzyme (FpGalNase, AC P0DTR5). Works on many different A antigen subtypes. Glu-90 probably act ... More
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A type blood N-acetyl-alpha-D-galactosamine deacetylase

Molecular Synopsis