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RPO132 (DNA-directed RNA polymerase 133 kDa polypeptide)
FEATURES
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FAMILY
DESCRIPTION
Also known as RP132_VARV, RPO132. Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity). The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits (147) kDa, (133) kDa, (35) kDa, (30) kDa, (22) kDa, (19) kDa, (18) kDa and (7) kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression (By similarity).
Also known as RP132_VARV, RPO132. Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) there ... More
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RPO132

DNA-directed RNA polymerase 133 kDa polypeptide

Molecular Synopsis