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(Basic phospholipase A2 CM-I)
FEATURES
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FAMILY
DESCRIPTION
Also known as PA2B1_NAJNG. Snake venom phospholipase A2 (PLA2) that shows weak anticoagulant activity. Is more catalytically active than the strong anticoagulant protein CM-IV found in this venom. Acts by inhibiting the complex composed of tissue factor (F3) and coagulation factor VIIa (F7) (TF-VIIa complex) by only enzymatic mechanism (PubMed:8866616). PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Also known as PA2B1_NAJNG. Snake venom phospholipase A2 (PLA2) that shows weak anticoagulant activity. Is more catalytically active than the strong anticoagulant protein CM-IV found in this venom. Acts by inhibiting the complex composed of tissue factor (F3) and coagulation factor VIIa (F7) (TF-VIIa complex) by only enzymatic mechanism (PubMed:8866 ... More
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Basic phospholipase A2 CM-I

Molecular Synopsis