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(Acidic phospholipase A2 Tpu-E6c)
FEATURES
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FAMILY
DESCRIPTION
Also known as PA2AC_TRIPE. Snake venom phospholipase A2 (PLA2) that impairs hemostasis. It weakly inhibits ADP-induced platelet aggregation when tested on platelet rich plasma from human and rabbit blood (15-25% of inhibition at 5-10 ug of enzyme), and dose-dependently inhibits blood coagulation, possibly by inhibiting thrombin activation. Exhibits high hydrolytic activities toward L-dipalmitoyl phosphatidylcholine. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Monomer.
Also known as PA2AC_TRIPE. Snake venom phospholipase A2 (PLA2) that impairs hemostasis. It weakly inhibits ADP-induced platelet aggregation when tested on platelet rich plasma from human and rabbit blood (15-25% of inhibition at 5-10 ug of enzyme), and dose-dependently inhibits blood coagulation, possibly by inhibiting thrombin activation. Exhibits ... More
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Acidic phospholipase A2 Tpu-E6c

Molecular Synopsis