doxB (Naphthalene 1, 2-dioxygenase system, large oxygenase component)

FEATURES

FAMILY

bacterial ring-hydroxylating dioxygenase alpha subunit family

DESCRIPTION

Also known as NDOB_PSEU8, doxB. Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-(1R, 2S)-dihydroxy-1, 2-dihydronaphthalene. The alpha subunit has a catalytic role in the holoenzyme. The naphthalene dioxygenase (NDO) multicomponent enzyme system is composed of an electron transfer component and a dioxygenase component (iron sulfur protein (ISP)). The electron transfer component is composed of a ferredoxin reductase and a ferredoxin (DoxA), and the dioxygenase component is formed of a heterohexamer (trimer of heterodimers) of three large alpha subunits (DoxB) and three small beta subunits (DoxD).

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EXTERNAL LINKS

doxB

Naphthalene 1, 2-dioxygenase system, large oxygenase component

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

doxB

Molecular Synopsis