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IGF1R (Insulin-like growth factor 1 receptor)
FEATURES
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FAMILY
Tyr protein kinase family
DESCRIPTION
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EXTERNAL LINKS
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IGF1R
Insulin-like growth factor 1 receptor
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MOLECULAR SYNOPSIS
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STRUCTURAL LIGANDABILITY
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CANCER TYPES
Cancer Types
Adrenal Cancer
Bile duct Cancer
Bladder Cancer
Bone Cancer
Bowel Cancer
Brain Tumour
Breast Cancer
Central Nervous System Cancer
Cervical Cancer
Endometrial Cancer
Eye Cancer
Female Cancers
Head and Neck Cancer
Kidney Cancer
Leukemia
Liver Cancer
Lung Cancer
Lymphoma
Male Cancers
Mesothelioma
Mouth and oropharyngeal Cancer
Multiple Myeloma
Neuroblastoma
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer
Salivary Gland Cancer
Skin Cancer
Soft Tissue Cancer
Stomach Cancer
Thyroid Cancer
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Molecular Synopsis
LIGANDABILITY
APPROVED DRUGS
Mecasermin
INVESTIGATIONAL DRUGS
XL-228
BMS-754807
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CHEMICAL PROBES
STRUCTURAL LIGANDABILITY
Identifies possible pockets on a protein 3D-structure and assesses the likely ligandability of the pocket
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NETWORK-BASED
Predicts the likely ligandability of a protein based on topological properties of the protein-protein interaction network
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CANCER SCORE
OTHER DISEASES SCORE
CHEMISTRY-BASED
Assesses the likely ligandability of a protein based on the chemical properties of compounds tested against the protein itself and/or its homologues
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CHEMISTRY-BASED SCORE
ANTIBODY-BASED
We predicted your protein as secreted one. This target is suitable for antibody therapy.
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