Chrna1 (Acetylcholine receptor subunit alpha)

FEATURES

FAMILY

ligand-gated ion channel (TC 1.A.9) family

DESCRIPTION

Also known as ACHA_MOUSE, Chrna1, Acra. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains (PubMed:17643119). The muscle heteropentamer composed of alpha-1, beta-1, delta, epsilon subunits interacts with the alpha-conotoxin ImII (By similarity).

... More

EXTERNAL LINKS

Chrna1

Acetylcholine receptor subunit alpha

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

Chrna1

Molecular Synopsis