FEATURES

DESCRIPTION

Also known as SHBG_HUMAN, SHBG. Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. Homodimer.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

SHBG

Sex hormone-binding globulin

ligandability Mutations

SHBG

Molecular Synopsis