CA2 (Carbonic anhydrase 2)

FEATURES

FAMILY

DESCRIPTION

Also known as CAH2_HUMAN, CA2. Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. Interacts with SLC4A4. Interaction with SLC4A7 regulates SLC4A7 transporter activity. Interacts with SLC26A6 isoform 4 (via C-terminus cytoplasmic domain).

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EXTERNAL LINKS

CA2

Carbonic anhydrase 2

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

CA2

Molecular Synopsis