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DAD1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1)
FEATURES
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FAMILY
DESCRIPTION
Also known as DAD1_MAIZE, DAD1. Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Component of the oligosaccharyltransferase (OST) complex.
Also known as DAD1_MAIZE, DAD1. Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein ... More
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DAD1

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

Molecular Synopsis