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dco (Discs overgrown protein kinase)
FEATURES
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FAMILY
DESCRIPTION
Also known as DCO_DROME, dco, dbt. Involved in circadian rhythms, viability and molecular oscillations of the clock genes period (per) and timeless (tim). Dbt reduces the stability and thus the accumulation of monomeric per proteins, probably through phosphorylation. No evident circadian oscillation is detected in head. Together with CkIalpha, regulates processing of ci by phosphorylating it which promotes its binding to slmb, the F-box recognition component of the SCF(slmb) E3 ubiquitin-protein ligase (PubMed:16326393). Forms a complex with per (PubMed:9674431). Interacts with Dlish (PubMed:27692068).
Also known as DCO_DROME, dco, dbt. Involved in circadian rhythms, viability and molecular oscillations of the clock genes period (per) and timeless (tim). Dbt reduces the stability and thus the accumulation of monomeric per proteins, probably through phosphorylation. No evident circadian oscillation is detected in head. Together with CkIalpha, regu ... More
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dco

Discs overgrown protein kinase

Molecular Synopsis