FEATURES

FAMILY

DESCRIPTION

Also known as NDUS2_HUMAN, NDUFS2. Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:12611891). Complex I is composed of 45 different subunits. Component of the iron-sulfur (IP) fragment of the enzyme (PubMed:12611891). Interacts with NDUFAF3 (PubMed:19463981). Interacts with NDUFAF7 (PubMed:20406883, PubMed:24089531).

... More

EXTERNAL LINKS

NDUFS2

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

ligandability Mutations

NDUFS2

Molecular Synopsis