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CACNA1B (Voltage-dependent N-type calcium channel subunit alpha-1B)
FEATURES
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FAMILY
DESCRIPTION
Also known as CAC1B_CHICK, CACNA1B. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons (By similarity). Multisubunit complex consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity. Interacts with RIMBP2.
Also known as CAC1B_CHICK, CACNA1B. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons (By similarity). Multisubunit complex consisting of alpha-1, alpha-2, beta ... More
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CACNA1B

Voltage-dependent N-type calcium channel subunit alpha-1B

Molecular Synopsis