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Ogg1 (N-glycosylase/DNA lyase)
FEATURES
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FAMILY
DESCRIPTION
Also known as OGG1_RAT, Ogg1, Mmh, Ogh1. DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
Also known as OGG1_RAT, Ogg1, Mmh, Ogh1. DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
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Ogg1

N-glycosylase/DNA lyase

Molecular Synopsis