FEATURES

FAMILY

DESCRIPTION

Also known as MMP20_HUMAN, MMP20. Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MMP20

Matrix metalloproteinase-20

MMP20

Molecular Synopsis