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GMDS (GDP-mannose 4,6 dehydratase)
FEATURES
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FAMILY
DESCRIPTION
Also known as GMDS_HUMAN, GMDS. Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
Also known as GMDS_HUMAN, GMDS. Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
GMDS logo

GMDS

GDP-mannose 4,6 dehydratase

Copy number variation

DiseaseSignal Cell linesGain Cell linesAvg. ampLoss Cell linesAvg. lossNo-signal Cell linesAvg. change
cancer 0 0 0 146 1.01
NS 0 0 0 153 0.99
carcinoma 5 1 1.90 4 0.15 546 1.02
haematopoietic_neoplasm 1 1 2.99 0 61 1.03
leukaemia 1 1 2.99 0 81 1.04
lymphoid_neoplasm 2 1 2.99 1 0.30 132 1.06
glioma 1 1 2.03 0 51 1.07
malignant_melanoma 0 0 0 56 1.18
melanoma 0 0 0 43 1.18
glioblastoma 0 0 0 2 0.85

Cell lines

Cell lineSignalCopy numberAvg. genome ploidyAmplificationDiseaseTissue
22Rv-1 No signal 2 2.04 0.98 cancer, NS, carcinoma prostate
5637 No signal 2 2.99 0.67 cancer, carcinoma bladder, urinary_tract
639-V No signal 3 2.41 1.25 cancer, carcinoma bladder, ureter, urinary_tract
647-V No signal 4 2.50 1.60 cancer, carcinoma bladder, urinary_tract
697 No signal 2 1.98 1.01 haematopoietic_neoplasm, leukaemia, lymphoid_neoplasm blood_bone_marrow, haematopoietic_and_lymphoid_tissue
769-P No signal 2 1.97 1.02 carcinoma kidney
786-0 No signal 4 3.82 1.05 cancer, carcinoma kidney
8-MG-BA No signal 3 2.20 1.37 glioma brain, central_nervous_system
8305C No signal 3 3.09 0.97 carcinoma thyroid
8505C No signal 3 3.00 1.00 carcinoma thyroid