FEATURES

FAMILY

DESCRIPTION

Also known as DHX16_HUMAN, DHX16, DBP2, DDX16, KIAA0577, PRP2. Required for pre-mRNA splicing as component of the spliceosome (PubMed:20423332, PubMed:20841358, PubMed:25296192, PubMed:29360106). Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. Component of pre-catalytic spliceosome complexes (PubMed:20423332, PubMed:20841358, PubMed:25296192, PubMed:29360106). Interacts with GPKOW.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

DHX16

Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

ligandability Mutations

DHX16

Molecular Synopsis