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Polr1b (DNA-directed RNA polymerase I subunit RPA2)
FEATURES
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FAMILY
DESCRIPTION
Also known as RPA2_RAT, Polr1b, Rpa2, Rpo1-2. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
Also known as RPA2_RAT, Polr1b, Rpa2, Rpo1-2. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the poly ... More
Polr1b logo

Polr1b

DNA-directed RNA polymerase I subunit RPA2

Molecular Synopsis