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esxG (ESAT-6-like protein EsxG)
FEATURES
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FAMILY
DESCRIPTION
Also known as ESXG_MYCTU, esxG. EsxG, in complex with EsxH, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery. EsxG stabilizes EsxH in the host cytosol. Forms a tight 1:1 complex with EsxH.
Also known as ESXG_MYCTU, esxG. EsxG, in complex with EsxH, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery. EsxG stabili ... More
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esxG

ESAT-6-like protein EsxG

Molecular Synopsis