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wts-1 (Serine/threonine-protein kinase WARTS homolog)
FEATURES
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FAMILY
DESCRIPTION
Also known as WARTS_CAEEL, wts-1. Phosphorylates yap-1 which may negatively regulate yap-1 nuclear localization (PubMed:23396260). Plays an essential role in larval development (PubMed:19737560, PubMed:19605499). Regulates growth, the formation of gut granules, lifespan and cell and body sizes probably in synergy with the TGF-beta sma/mab pathway (PubMed:19737560). Does not appear to regulate apoptosis and proliferation (PubMed:19605499). In addition, may synergize with the TGF-beta daf-7 dauer pathway to regulate entry into the dauer stage (PubMed:19737560). Maintains the cellular integrity of intestinal cells by regulating the localization of apical actin and junctional proteins (PubMed:19605499). Interacts (via N-terminus) with yap-1 (via WW domain).
Also known as WARTS_CAEEL, wts-1. Phosphorylates yap-1 which may negatively regulate yap-1 nuclear localization (PubMed:23396260). Plays an essential role in larval development (PubMed:19737560, PubMed:19605499). Regulates growth, the formation of gut granules, lifespan and cell and body sizes probably in synergy with the TGF-beta sma/mab pathway ( ... More
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wts-1

Serine/threonine-protein kinase WARTS homolog

Molecular Synopsis