ALOX15B (Arachidonate 15-lipoxygenase B)
FEATURES
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DESCRIPTION
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EXTERNAL LINKS
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Germline Genetics

Summary of germline evidence for ALOX15B and cancer

  • Ensembl Gene ID: ENSG00000179593
  • Ensembl Transcript ID/s: ENST00000380173; ENST00000380183; ENST00000573359
  • Entrez Gene ID: 247
  • HGNC Gene Symbol: ALOX15B

Genome-wide association studies

ALOX15B maps to cancer-SNP associations according to the following annotations:

SNPLocusPosition (b37)Risk alleleRAFP-valueEffect sizeCICancerPMIDCatalogTADLSDEPICT
783_rs164276417p13.17557834rs1642764-C0.5013E-131.14[1.1-1.18]Esophageal squamous cell carcinoma25129146https://www.ebi.ac.uk/gwas/search?query=rs164276417:7500000-8140000--
1109_rs3585075317p13.17578671rs35850753-T0.0201671E-81.9466[1.57-2.43]Sporadic neuroblastoma28545128https://www.ebi.ac.uk/gwas/search?query=rs3585075317:7500000-8140000r2>0.2 (17:7087658-7954764)-
1658_rs3585075317p13.17578671rs35850753-TNR9E-202.53[2.07-3.08]Glioma26424050https://www.ebi.ac.uk/gwas/search?query=rs3585075317:7500000-8140000r2>0.2 (17:7087658-7954764)-
1665_rs3585075317p13.17578671rs35850753-TNR4E-122.79[2.09-3.72]Glioblastoma26424050https://www.ebi.ac.uk/gwas/search?query=rs3585075317:7500000-8140000r2>0.2 (17:7087658-7954764)-
1594_rs7837822217p13.17571752rs78378222-G0.0181E-202.07[NR]Basal cell carcinoma25855136https://www.ebi.ac.uk/gwas/search?query=rs7837822217:7500000-8140000r2>0.1 (17:7084610-8030090)-
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