spc34 (DASH complex subunit spc34)

FEATURES

FAMILY

DESCRIPTION

Also known as SPC34_SCHPO, spc34. Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. The DASH complex oligomerizes to form rings that encircle the microtubules.

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EXTERNAL LINKS

spc34

DASH complex subunit spc34

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

spc34

Molecular Synopsis