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Necab2 (N-terminal EF-hand calcium-binding protein 2)
FEATURES
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DESCRIPTION
Also known as NECA2_RAT, Necab2, Efcbp2. May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation. Interacts (calcium-dependent) with ADORA2A and GRM5.
Also known as NECA2_RAT, Necab2, Efcbp2. May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation. Interacts (calcium-dependent) with ADORA2 ... More
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Necab2

N-terminal EF-hand calcium-binding protein 2

Molecular Synopsis