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Irf2bp2 (Interferon regulatory factor 2-binding protein 2)
FEATURES
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FAMILY
DESCRIPTION
Also known as I2BP2_MOUSE, Irf2bp2. Acts as a transcriptional corepressor in a IRF2-dependent manner, this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation (By similarity). Interacts with IRF2. Part of a corepressor complex containing IRF2 and IRF2BP1. Interacts with VGLL4 (By similarity).
Also known as I2BP2_MOUSE, Irf2bp2. Acts as a transcriptional corepressor in a IRF2-dependent manner, this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cel ... More
Irf2bp2 logo

Irf2bp2

Interferon regulatory factor 2-binding protein 2

Molecular Synopsis