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MARF1 (Meiosis regulator and mRNA stability factor 1)
FEATURES
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DESCRIPTION
Also known as MARF1_BOVIN, MARF1, LKAP. Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity). Interacts with LIMK2.
Also known as MARF1_BOVIN, MARF1, LKAP. Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of tr ... More
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MARF1

Meiosis regulator and mRNA stability factor 1

Molecular Synopsis