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BRAT1 (BRCA1-associated ATM activator 1)
FEATURES
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DESCRIPTION
Also known as BRAT1_AILME, BRAT1, BAAT1. Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Plays a role in regulating mitochondrial function and cell proliferation. Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors. Interacts with BRCA1 and ATM. Interacts with MTOR, RPTOR, NDFIP1, SMC1A and PRKDC.
Also known as BRAT1_AILME, BRAT1, BAAT1. Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Plays a role in regulating mitochondrial function and cell proliferation. Required for protein stability of MTOR and MTOR-related proteins, and cell cyc ... More
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BRAT1

BRCA1-associated ATM activator 1

Molecular Synopsis