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Usp36 (Ubiquitin carboxyl-terminal hydrolase 36)
FEATURES
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FAMILY
DESCRIPTION
Also known as UBP36_DROSI, Usp36, scny. Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4). Controls selective autophagy activation by ubiquitinated proteins. Interacts with atms/PAF1, but not with CycT.
Also known as UBP36_DROSI, Usp36, scny. Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby prev ... More
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Usp36

Ubiquitin carboxyl-terminal hydrolase 36

Molecular Synopsis