eIF3d1 (Eukaryotic translation initiation factor 3 subunit D-1)

FEATURES

FAMILY

DESCRIPTION

Also known as EI3D1_DROVI, eIF3d1, eIF-3p66. mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix.

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EXTERNAL LINKS

eIF3d1

Eukaryotic translation initiation factor 3 subunit D-1

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

eIF3d1

Molecular Synopsis